Police were at the Ludington Rite Aid early Tuesday afternoon after a bomb threat was called in to the store.
The Mason County Sheriff's Office asked that citizens avoid the area of Jackson Street and US 10, where Rite-Aid is located, as law enforcement officers investigated.
The scene was cleared about 2:15 p.m.
The call came in to the store, according to Ludington Police Chief Mark Barnett, and threats have been made regarding other Rite-Aids as well.
Officer Dave Rodriguez of the Little River Band of Ottawa Indians and police dog Edo helped at the Ludington scene.
The building was evacuated after the call came in about 12:30 p.m.
There were nine employees at the Ludington store, with most of them at the EZ Mart across the street while the manager helped police and the investigation was ongoing at the scene.
The roads adjacent to the store remained open and traffic continued to flow with the exception of a two-car accident caused by an allegedly drunk driver on Ludington Avenue just west of Jackson Avenue.